Mefenamic acid in urinary retention.

Mefenamic acid enteropathy.

The clinical, radiological, and histological features of two patients with severe intestinal damage induced by mefenamic acid and mimicking coeliac disease are described. Symptoms rapidly reverted on withdrawal of the drug, and in one case, did not relapse during treatment with other non-steroidal anti-inflammatory drugs.

Mefenamic acid-induced bullous pemphigoid.

A 52 year old man developed bullous pemphigoid, Coombs' positive haemolytic anaemia and diarrhoea related to the use of mefenamic acid. Clinical manifestation of the bullous pemphigoid, haemolytic anaemia and diarrhoea resolved following discontinuation of the mefenamic acid. Mefenamic acid should be added to the list of agents that are known to induce bullous pemphigoid.

Spherical Crystallization of Mefenamic Acid

*To whom all correspondence should be addressed. he quality of a solid pharmaceutical preparation is influenced by primary micromeritic characteristics such as the shape and size of drug crystals, especially when large amounts of poorly soluble drugs are formulated. To improve the dissolution rate of poorly soluble drugs, fine crystals are preferred over large crystals because they provide a gr...

Urinary retention in women.

Mefenamic Acid induced nephrotoxicity: an animal model.

PURPOSE Nonsteroidal anti-inflammatory drugs (NSAIDs) are used for the treatment of many joint disorders, inflammation and to control pain. Numerous reports have indicated that NSAIDs are capable of producing nephrotoxicity in human. Therefore, the objective of this study was to evaluate mefenamic acid, a NSAID nephrotoxicity in an animal model. METHODS Mice were dosed intraperitoneally with ...